A CDC20-APC/SOX2 Signaling Axis Regulates Human Glioblastoma Stem-Like Cells

Glioblastoma harbors a dynamic subpopulation of glioblastoma stem-like cells (GSCs) that can propagate tumors in vivo and is resistant to standard chemoradiation. Identification of the cell-intrinsic mechanisms governing this clinically important cell state may lead to the discovery of novel therape...

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Publicado en:Cell Rep
Main Authors: Mao, Diane D, Gujar, Amit D, Mahlokozera, Tatenda, Chen, Ishita, Pan, Yanchun, Luo, Jingqin, Brost, Taylor, Thompson, Elizabeth A, Turski, Alice, Leuthardt, Eric C, Dunn, Gavin P, Chicoine, Michael R, Rich, Keith M, Dowling, Joshua L, Zipfel, Gregory J, Dacey, Ralph G, Achilefu, Samuel, Tran, David D, Yano, Hiroko, Kim, Albert H
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481182/
https://ncbi.nlm.nih.gov/pubmed/26074073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.05.027
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