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STEM-07. NON-CANONICAL REGULATION OF SOX2 BY THE TRIM26 E3 UBIQUITIN LIGASE IN GLIOBLASTOMA STEM-LIKE CELLS
Ubiquitin-dependent signaling is critical for the regulation of glioblastoma stem-like cells (GSCs), a subpopulation of glioblastoma cells responsible for tumor growth and therapy resistance. TRIM26, an E3-ubiquitin ligase with immune-related functions, is highly expressed in glioblastoma tumors com...
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| 發表在: | Neuro Oncol |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6216523/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.1014 |
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