Cooperation between somatic mutations and germline susceptibility variants in tumorigenesis – a dangerous liaison

High-throughput genotyping and sequencing generate comprehensive catalogs of inherited genetic variations and acquired somatic mutations. However, their possible interactions and roles in tumorigenesis remain largely unexplored. We recently reported cooperation between the EWSR1-FLI1 (Ewing sarcoma...

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Bibliographic Details
Published in:Mol Cell Oncol
Main Authors: Grünewald, Thomas G. P., Delattre, Olivier
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909413/
https://ncbi.nlm.nih.gov/pubmed/27314638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1086853
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