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Germline variants impact on somatic events during tumorigenesis

Cancer is characterized by diverse genetic alterations in both germline and somatic genomes that disrupt normal biology and providea selective advantage to cells during tumorigenesis. Germline and somatic genomes have been extensively studied independently, leading to numerous biological insights. A...

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Bibliografiska uppgifter
I publikationen:Trends Genet
Huvudupphovsmän: Ramroop, Johnny R., Gerber, Madelyn M., Toland, Amanda Ewart
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6571050/
https://ncbi.nlm.nih.gov/pubmed/31128889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2019.04.005
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