Germline Variation Controls the Architecture of Somatic Alterations in Tumors

Studies have suggested that somatic events in tumors can depend on an individual's constitutional genotype. We used squamous cell carcinomas (SCC) of the skin, which arise in high multiplicity in organ transplant recipients, as a model to compare the pattern of somatic alterations within and ac...

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Autors principals: Dworkin, Amy M., Ridd, Katie, Bautista, Dianne, Allain, Dawn C., Iwenofu, O. Hans, Roy, Ritu, Bastian, Boris C., Toland, Amanda Ewart
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944791/
https://ncbi.nlm.nih.gov/pubmed/20885788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001136
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