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Germline variants impact on somatic events during tumorigenesis
Cancer is characterized by diverse genetic alterations in both germline and somatic genomes that disrupt normal biology and providea selective advantage to cells during tumorigenesis. Germline and somatic genomes have been extensively studied independently, leading to numerous biological insights. A...
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| Udgivet i: | Trends Genet |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6571050/ https://ncbi.nlm.nih.gov/pubmed/31128889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2019.04.005 |
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