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Drosophila Aurora A regulates mitotic timing in cancer stem cells: Possible therapeutic implications

Loss of Aurora A in Drosophila neuroblasts promotes loss of cell fate, leading to brain tumors. We showed that these tumor stem cells are delayed during mitosis and efficiently segregate their chromosomes even without the spindle assembly checkpoint. Here, we discuss the possible relevance of our re...

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Bibliografiske detaljer
Udgivet i:Mol Cell Oncol
Main Authors: Caous, Renaud, Richard-Parpaillon, Laurent, Giet, Régis
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909412/
https://ncbi.nlm.nih.gov/pubmed/27314090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2016.1140261
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