Drosophila Aurora A regulates mitotic timing in cancer stem cells: Possible therapeutic implications

Loss of Aurora A in Drosophila neuroblasts promotes loss of cell fate, leading to brain tumors. We showed that these tumor stem cells are delayed during mitosis and efficiently segregate their chromosomes even without the spindle assembly checkpoint. Here, we discuss the possible relevance of our re...

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Vydáno v:Mol Cell Oncol
Hlavní autoři: Caous, Renaud, Richard-Parpaillon, Laurent, Giet, Régis
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909412/
https://ncbi.nlm.nih.gov/pubmed/27314090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2016.1140261
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