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Therapeutic potential of mitotic interaction between the nucleoporin Tpr and aurora kinase A

Spindle poles are defined by centrosomes; therefore, an abnormal number or defective structural organization of centrosomes can lead to loss of spindle bipolarity and genetic integrity. Previously, we showed that Tpr (translocated promoter region), a component of the nuclear pore complex (NPC), inte...

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Vydáno v:Cell Cycle
Hlavní autoři: Kobayashi, Akiko, Hashizume, Chieko, Dowaki, Takayuki, Wong, Richard W
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614903/
https://ncbi.nlm.nih.gov/pubmed/25789545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1021518
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