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Down-modulation of nucleoporin RanBP2/Nup358 impaired chromosomal alignment and induced mitotic catastrophe

Chromosomal missegregation is a common feature of many human tumors. Recent studies have indicated a link between nucleoporin RanBP2/Nup358 and chromosomal segregation during mitosis; however, the molecular details have yet to be fully established. Observed through live cell imaging and flow cytomet...

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Autori principali: Hashizume, C, Kobayashi, A, Wong, R W
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3824679/
https://ncbi.nlm.nih.gov/pubmed/24113188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.370
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