Nucleoporin Translocated Promoter Region (Tpr) Associates with Dynein Complex, Preventing Chromosome Lagging Formation during Mitosis

Gain or loss of whole chromosomes is often observed in cancer cells and is thought to be due to aberrant chromosome segregation during mitosis. Proper chromosome segregation depends on a faithful interaction between spindle microtubules and kinetochores. Several components of the nuclear pore comple...

Full description

Saved in:
Bibliographic Details
Main Authors: Nakano, Hiroshi, Funasaka, Tatsuyoshi, Hashizume, Chieko, Wong, Richard W.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856290/
https://ncbi.nlm.nih.gov/pubmed/20133940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.105890
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items