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Nucleoporin Translocated Promoter Region (Tpr) Associates with Dynein Complex, Preventing Chromosome Lagging Formation during Mitosis

Gain or loss of whole chromosomes is often observed in cancer cells and is thought to be due to aberrant chromosome segregation during mitosis. Proper chromosome segregation depends on a faithful interaction between spindle microtubules and kinetochores. Several components of the nuclear pore comple...

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Autors principals: Nakano, Hiroshi, Funasaka, Tatsuyoshi, Hashizume, Chieko, Wong, Richard W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856290/
https://ncbi.nlm.nih.gov/pubmed/20133940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.105890
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