Colorectal cancer cells require glycogen synthase kinase-3β for sustaining mitosis via translocated promoter region (TPR)-dynein interaction

Glycogen synthase kinase (GSK) 3β, which mediates fundamental cellular signaling pathways, has emerged as a potential therapeutic target for many types of cancer including colorectal cancer (CRC). During mitosis, GSK3β localizes in mitotic spindles and centrosomes, however its function is largely un...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Dewi, Firli R.P., Domoto, Takahiro, Hazawa, Masaharu, Kobayashi, Akiko, Douwaki, Takayuki, Minamoto, Toshinari, Wong, Richard W.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862582/
https://ncbi.nlm.nih.gov/pubmed/29568361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24344
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