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Spindle assembly checkpoint inactivation fails to suppress neuroblast tumour formation in aurA mutant Drosophila

Tissue homeostasis requires accurate control of cell proliferation, differentiation and chromosome segregation. Drosophila sas-4 and aurA mutants present brain tumours with extra neuroblasts (NBs), defective mitotic spindle assembly and delayed mitosis due to activation of the spindle assembly check...

詳細記述

保存先:
書誌詳細
出版年:Nat Commun
主要な著者: Caous, Renaud, Pascal, Aude, Romé, Pierre, Richard-Parpaillon, Laurent, Karess, Roger, Giet, Régis
フォーマット: Artigo
言語:Inglês
出版事項: Nature Pub. Group 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4660220/
https://ncbi.nlm.nih.gov/pubmed/26568519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9879
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