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Drosophila Aurora A regulates mitotic timing in cancer stem cells: Possible therapeutic implications

Loss of Aurora A in Drosophila neuroblasts promotes loss of cell fate, leading to brain tumors. We showed that these tumor stem cells are delayed during mitosis and efficiently segregate their chromosomes even without the spindle assembly checkpoint. Here, we discuss the possible relevance of our re...

詳細記述

保存先:
書誌詳細
出版年:Mol Cell Oncol
主要な著者: Caous, Renaud, Richard-Parpaillon, Laurent, Giet, Régis
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909412/
https://ncbi.nlm.nih.gov/pubmed/27314090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2016.1140261
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