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Retinal degeneration is rescued in transgenic rd mice by expression of the cGMP phosphodiesterase beta subunit.

The beta subunit of the cGMP phosphodiesterase (PDE) gene has been identified as the candidate gene for retinal degeneration in the rd mouse. To study the molecular mechanisms underlying degeneration and the potential for gene repair, we have expressed a functional bovine cGMP PDE beta subunit in tr...

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Bibliografske podrobnosti
Main Authors: Lem, J, Flannery, J G, Li, T, Applebury, M L, Farber, D B, Simon, M I
Format: Artigo
Jezik:Inglês
Izdano: 1992
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC49094/
https://ncbi.nlm.nih.gov/pubmed/1350091
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