Retinal Degeneration in Mice Lacking the γ Subunit of the Rod cGMP Phosphodiesterase

The retinal cyclic guanosine 3′,5′-monophosphate (cGMP) phosphodiesterase (PDE) is a key regulator of phototransduction in the vertebrate visual system. PDE consists of a catalytic core of α and β subunits associated with two inhibitory γ subunits. A gene-targeting approach was used to disrupt the m...

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Detaylı Bibliyografya
Asıl Yazarlar: Tsang, Stephen H., Gouras, Peter, Yamashita, Clyde K., Kjeldbye, Hild, Fisher, John, Farber, Debora B., Gofft, Stephen P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1996
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757426/
https://ncbi.nlm.nih.gov/pubmed/8638127
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