Two mouse retinal degenerations caused by missense mutations in the beta-subunit of rod cGMP phosphodiesterase gene

We report the chromosomal localization, mutant gene identification, ophthalmic appearance, histology, and functional analysis of two new hereditary mouse models of retinal degeneration not having the Pde6b(rd1) (“r”, “rd”, or “rodless”) mutation. One strain harbors an autosomal recessive mutation th...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Chang, B., Hawes, N.L., Pardue, M. T., German, A.M., Hurd, R.E., Davisson, M.T., Nusinowitz, S., Rengarajan, K., Boyd, A.P., Starr, S.S., Chaudhury, R.C., Nickerson, J.M., Heckenlively, J.R., Boatright, J.H
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2007
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562796/
https://ncbi.nlm.nih.gov/pubmed/17267005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.visres.2006.11.020
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