Two mouse retinal degenerations caused by missense mutations in the beta-subunit of rod cGMP phosphodiesterase gene

We report the chromosomal localization, mutant gene identification, ophthalmic appearance, histology, and functional analysis of two new hereditary mouse models of retinal degeneration not having the Pde6b(rd1) (“r”, “rd”, or “rodless”) mutation. One strain harbors an autosomal recessive mutation th...

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Main Authors: Chang, B., Hawes, N.L., Pardue, M. T., German, A.M., Hurd, R.E., Davisson, M.T., Nusinowitz, S., Rengarajan, K., Boyd, A.P., Starr, S.S., Chaudhury, R.C., Nickerson, J.M., Heckenlively, J.R., Boatright, J.H
格式: Artigo
語言:Inglês
出版: 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562796/
https://ncbi.nlm.nih.gov/pubmed/17267005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.visres.2006.11.020
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