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Structure of the I-SceI nuclease complexed with its dsDNA target and three catalytic metal ions

Homing endonucleases are highly specific DNA-cleaving enzymes that recognize and cleave long stretches of DNA. The engineering of these enzymes provides instruments for genome modification in a wide range of fields, including gene targeting. The homing endonuclease I-SceI from the yeast Saccharomyce...

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Библиографические подробности
Опубликовано в: :Acta Crystallogr F Struct Biol Commun
Главные авторы: Prieto, Jesús, Redondo, Pilar, Merino, Nekane, Villate, Maider, Montoya, Guillermo, Blanco, Francisco J., Molina, Rafael
Формат: Artigo
Язык:Inglês
Опубликовано: International Union of Crystallography 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909248/
https://ncbi.nlm.nih.gov/pubmed/27303901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X16007512
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