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Structure of the I-SceI nuclease complexed with its dsDNA target and three catalytic metal ions
Homing endonucleases are highly specific DNA-cleaving enzymes that recognize and cleave long stretches of DNA. The engineering of these enzymes provides instruments for genome modification in a wide range of fields, including gene targeting. The homing endonuclease I-SceI from the yeast Saccharomyce...
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Опубликовано в: : | Acta Crystallogr F Struct Biol Commun |
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Главные авторы: | , , , , , , |
Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
International Union of Crystallography
2016
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4909248/ https://ncbi.nlm.nih.gov/pubmed/27303901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X16007512 |
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