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Structure of the I-SceI nuclease complexed with its dsDNA target and three catalytic metal ions
Homing endonucleases are highly specific DNA-cleaving enzymes that recognize and cleave long stretches of DNA. The engineering of these enzymes provides instruments for genome modification in a wide range of fields, including gene targeting. The homing endonuclease I-SceI from the yeast Saccharomyce...
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| Gepubliceerd in: | Acta Crystallogr F Struct Biol Commun |
|---|---|
| Hoofdauteurs: | , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
International Union of Crystallography
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4909248/ https://ncbi.nlm.nih.gov/pubmed/27303901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X16007512 |
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