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Data-driven mechanistic analysis method to reveal dynamically evolving regulatory networks

Motivation: Mechanistic models based on ordinary differential equations provide powerful and accurate means to describe the dynamics of molecular machinery which orchestrates gene regulation. When combined with appropriate statistical techniques, mechanistic models can be calibrated using experiment...

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Bibliografske podrobnosti
izdano v:Bioinformatics
Main Authors: Intosalmi, Jukka, Nousiainen, Kari, Ahlfors, Helena, Lähdesmäki, Harri
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908358/
https://ncbi.nlm.nih.gov/pubmed/27307629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw274
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