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Data-driven mechanistic analysis method to reveal dynamically evolving regulatory networks

Motivation: Mechanistic models based on ordinary differential equations provide powerful and accurate means to describe the dynamics of molecular machinery which orchestrates gene regulation. When combined with appropriate statistical techniques, mechanistic models can be calibrated using experiment...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Intosalmi, Jukka, Nousiainen, Kari, Ahlfors, Helena, Lähdesmäki, Harri
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908358/
https://ncbi.nlm.nih.gov/pubmed/27307629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw274
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