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Data-driven mechanistic analysis method to reveal dynamically evolving regulatory networks

Motivation: Mechanistic models based on ordinary differential equations provide powerful and accurate means to describe the dynamics of molecular machinery which orchestrates gene regulation. When combined with appropriate statistical techniques, mechanistic models can be calibrated using experiment...

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Détails bibliographiques
Publié dans:Bioinformatics
Auteurs principaux: Intosalmi, Jukka, Nousiainen, Kari, Ahlfors, Helena, Lähdesmäki, Harri
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908358/
https://ncbi.nlm.nih.gov/pubmed/27307629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw274
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