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Isoform-level ribosome occupancy estimation guided by transcript abundance with Ribomap

Summary: Ribosome profiling is a recently developed high-throughput sequencing technique that captures approximately 30 bp long ribosome-protected mRNA fragments during translation. Because of alternative splicing and repetitive sequences, a ribosome-protected read may map to many places in the tran...

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Bibliographic Details
Published in:Bioinformatics
Main Authors: Wang, Hao, McManus, Joel, Kingsford, Carl
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908323/
https://ncbi.nlm.nih.gov/pubmed/27153676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw085
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