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Accurate Recovery of Ribosome Positions Reveals Slow Translation of Wobble-Pairing Codons in Yeast

Ribosome profiling quantitatively captures ribosome locations during translation. The resulting profiles of ribosome locations are widely used to study translational speed. However, an accurate estimation of the ribosome location depends on identifying the A-site from ribosome profiling reads, a pro...

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Pubblicato in:J Comput Biol
Autori principali: Wang, Hao, McManus, Joel, Kingsford, Carl
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5467134/
https://ncbi.nlm.nih.gov/pubmed/27726445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2016.0147
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