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Accurate Recovery of Ribosome Positions Reveals Slow Translation of Wobble-Pairing Codons in Yeast

Ribosome profiling quantitatively captures ribosome locations during translation. The resulting profiles of ribosome locations are widely used to study translational speed. However, an accurate estimation of the ribosome location depends on identifying the A-site from ribosome profiling reads, a pro...

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Detalhes bibliográficos
Publicado no:J Comput Biol
Main Authors: Wang, Hao, McManus, Joel, Kingsford, Carl
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5467134/
https://ncbi.nlm.nih.gov/pubmed/27726445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2016.0147
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