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Accurate Recovery of Ribosome Positions Reveals Slow Translation of Wobble-Pairing Codons in Yeast

Ribosome profiling quantitatively captures ribosome locations during translation. The resulting profiles of ribosome locations are widely used to study translational speed. However, an accurate estimation of the ribosome location depends on identifying the A-site from ribosome profiling reads, a pro...

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Dades bibliogràfiques
Publicat a:J Comput Biol
Autors principals: Wang, Hao, McManus, Joel, Kingsford, Carl
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5467134/
https://ncbi.nlm.nih.gov/pubmed/27726445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2016.0147
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