Epigenetically Mediated Spontaneous Reduction of NFAT1 Expression Causes Imbalanced Metabolic Activities of Articular Chondrocytes in Aged Mice

OBJECTIVE: Abnormal metabolic activities of chondrocytes may cause articular cartilage (AC) degradation, but key transcription factors regulating metabolic activities in AC of aging individuals remain unknown. This study aimed to investigate the role of transcription factor NFAT1 in regulating the e...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Osteoarthritis Cartilage
Egile Nagusiak: Zhang, Mingcai, Lu, Qinghua, Egan, Brian, Zhong, Xiao-bo, Brandt, Kenneth, Wang, Jinxi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907852/
https://ncbi.nlm.nih.gov/pubmed/26903200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2016.02.003
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