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Nfat1 Regulates Adult Articular Chondrocyte Function through Its Age-Dependent Expression Mediated by Epigenetic Histone Methylation

The development of disease-modifying pharmacologic therapy for osteoarthritis (OA) currently faces major obstacles, largely because the regulatory mechanisms for the function of adult articular chondrocytes remain unclear. We previously demonstrated that lack of Nfat1, one of the NFAT (nuclear facto...

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Detalhes bibliográficos
Main Authors: Rodova, Marianna, Lu, Qinghua, Li, Ye, Woodbury, Brent G, Crist, Jamie D, Gardner, Brian M, Yost, John G, Zhong, Xiao-bo, Anderson, H Clarke, Wang, Jinxi
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353550/
https://ncbi.nlm.nih.gov/pubmed/21452283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.397
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