Epigenetically Mediated Spontaneous Reduction of NFAT1 Expression Causes Imbalanced Metabolic Activities of Articular Chondrocytes in Aged Mice

OBJECTIVE: Abnormal metabolic activities of chondrocytes may cause articular cartilage (AC) degradation, but key transcription factors regulating metabolic activities in AC of aging individuals remain unknown. This study aimed to investigate the role of transcription factor NFAT1 in regulating the e...

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Bibliografiset tiedot
Julkaisussa:Osteoarthritis Cartilage
Päätekijät: Zhang, Mingcai, Lu, Qinghua, Egan, Brian, Zhong, Xiao-bo, Brandt, Kenneth, Wang, Jinxi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907852/
https://ncbi.nlm.nih.gov/pubmed/26903200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2016.02.003
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