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Epigenetic mechanisms underlying the aberrant catabolic and anabolic activities of osteoarthritic chondrocytes

The development of disease-modifying pharmacologic therapy for osteoarthritis currently faces major obstacles largely because the pathogenetic mechanisms for development of osteoarthritis remain unclear. Previous studies suggest that the alterations in expression of catabolic and anabolic genes in a...

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Библиографические подробности
Опубликовано в: :Int J Biochem Cell Biol
Главные авторы: Zhang, Mingcai, Egan, Brian, Wang, Jinxi
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564332/
https://ncbi.nlm.nih.gov/pubmed/25975825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2015.04.019
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