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Epigenetic mechanisms underlying the aberrant catabolic and anabolic activities of osteoarthritic chondrocytes

The development of disease-modifying pharmacologic therapy for osteoarthritis currently faces major obstacles largely because the pathogenetic mechanisms for development of osteoarthritis remain unclear. Previous studies suggest that the alterations in expression of catabolic and anabolic genes in a...

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Detalhes bibliográficos
Publicado no:Int J Biochem Cell Biol
Main Authors: Zhang, Mingcai, Egan, Brian, Wang, Jinxi
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564332/
https://ncbi.nlm.nih.gov/pubmed/25975825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2015.04.019
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