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Epigenetic mechanisms underlying the aberrant catabolic and anabolic activities of osteoarthritic chondrocytes

The development of disease-modifying pharmacologic therapy for osteoarthritis currently faces major obstacles largely because the pathogenetic mechanisms for development of osteoarthritis remain unclear. Previous studies suggest that the alterations in expression of catabolic and anabolic genes in a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Biochem Cell Biol
Hauptverfasser: Zhang, Mingcai, Egan, Brian, Wang, Jinxi
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564332/
https://ncbi.nlm.nih.gov/pubmed/25975825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2015.04.019
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