Runx1 Activities in Superficial Zone Chondrocytes, Osteoarthritic Chondrocyte Clones and Response to Mechanical Loading

OBJECTIVE: Runx1, the hematopoietic lineage determining transcription factor, is present in perichondrium and chondrocytes. Here we addressed Runx1 functions, by examining expression in cartilage during mouse and human osteoarthritis (OA) progression and in response to mechanical loading. METHODS: S...

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Publicat a:J Cell Physiol
Autors principals: LeBlanc, Kimberly T., Walcott, Marie E., Gaur, Tripti, O’Connell, Shannon L., Basil, Kirti, Tadiri, Christina P., Mason-Savas, April, Silva, Jason A., van Wijnen, Andre J., Stein, Janet L., Stein, Gary S, Ayers, David C., Lian, Jane B., Fanning, Paul J.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420729/
https://ncbi.nlm.nih.gov/pubmed/25078095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24727
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