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Nfat1 Regulates Adult Articular Chondrocyte Function through Its Age-Dependent Expression Mediated by Epigenetic Histone Methylation

The development of disease-modifying pharmacologic therapy for osteoarthritis (OA) currently faces major obstacles, largely because the regulatory mechanisms for the function of adult articular chondrocytes remain unclear. We previously demonstrated that lack of Nfat1, one of the NFAT (nuclear facto...

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Dettagli Bibliografici
Autori principali: Rodova, Marianna, Lu, Qinghua, Li, Ye, Woodbury, Brent G, Crist, Jamie D, Gardner, Brian M, Yost, John G, Zhong, Xiao-bo, Anderson, H Clarke, Wang, Jinxi
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353550/
https://ncbi.nlm.nih.gov/pubmed/21452283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.397
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