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Gene Therapy for Immune Tolerance Induction in Hemophilia with Inhibitors
The development of inhibitors, neutralizing alloantibodies to Factor VIII (FVIII) or Factor IX (FIX), is the most significant complication of protein replacement therapy for patients with hemophilia and is associated with increased mortality as well as substantial physical, psychosocial, and financi...
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| Veröffentlicht in: | J Thromb Haemost |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4907803/ https://ncbi.nlm.nih.gov/pubmed/27061380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.13331 |
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