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Gene Therapy for Immune Tolerance Induction in Hemophilia with Inhibitors

The development of inhibitors, neutralizing alloantibodies to Factor VIII (FVIII) or Factor IX (FIX), is the most significant complication of protein replacement therapy for patients with hemophilia and is associated with increased mortality as well as substantial physical, psychosocial, and financi...

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Dettagli Bibliografici
Pubblicato in:J Thromb Haemost
Autori principali: Arruda, Valder R., Samelson-Jones, Ben J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907803/
https://ncbi.nlm.nih.gov/pubmed/27061380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.13331
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