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Obstacles and future of gene therapy for hemophilia

INTRODUCTION: The recent success of early-phase clinical trials for adeno-associated viral (AAV) liver-directed gene therapy for hemophilia B (HB) demonstrates the potential for gene therapy, in the future, to succeed protein-based prophylaxis therapy for HB. Significant obstacles, however, need to...

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Detalhes bibliográficos
Publicado no:Expert Opin Orphan Drugs
Main Authors: Arruda, Valder R, Samelson-Jones, Ben J
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756761/
https://ncbi.nlm.nih.gov/pubmed/26900534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/21678707.2015.1069179
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