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Gene Therapy for Immune Tolerance Induction in Hemophilia with Inhibitors

The development of inhibitors, neutralizing alloantibodies to Factor VIII (FVIII) or Factor IX (FIX), is the most significant complication of protein replacement therapy for patients with hemophilia and is associated with increased mortality as well as substantial physical, psychosocial, and financi...

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Detalhes bibliográficos
Publicado no:J Thromb Haemost
Main Authors: Arruda, Valder R., Samelson-Jones, Ben J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907803/
https://ncbi.nlm.nih.gov/pubmed/27061380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.13331
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