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Gene Therapy for Immune Tolerance Induction in Hemophilia with Inhibitors

The development of inhibitors, neutralizing alloantibodies to Factor VIII (FVIII) or Factor IX (FIX), is the most significant complication of protein replacement therapy for patients with hemophilia and is associated with increased mortality as well as substantial physical, psychosocial, and financi...

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Bibliografski detalji
Izdano u:J Thromb Haemost
Glavni autori: Arruda, Valder R., Samelson-Jones, Ben J.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907803/
https://ncbi.nlm.nih.gov/pubmed/27061380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.13331
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