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ALIX Regulates the Ubiquitin-Independent Lysosomal Sorting of the P2Y(1) Purinergic Receptor via a YPX(3)L Motif
Endocytic sorting and lysosomal degradation are integral to the regulation of G protein-coupled receptor (GPCR) function. Upon ligand binding, classical GPCRs are activated, internalized and recycled or sorted to lysosomes for degradation, a process that requires receptor ubiquitination. However, re...
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| Опубликовано в: : | PLoS One |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4907476/ https://ncbi.nlm.nih.gov/pubmed/27301021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157587 |
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