ALIX binds a YPX(3)L motif of the GPCR PAR1 and mediates ubiquitin-independent ESCRT-III/MVB sorting

The sorting of signaling receptors to lysosomes is an essential regulatory process in mammalian cells. During degradation, receptors are modified with ubiquitin and sorted by endosomal sorting complex required for transport (ESCRT)–0, –I, –II, and –III complexes into intraluminal vesicles (ILVs) of...

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Bibliografski detalji
Glavni autori: Dores, Michael R., Chen, Buxin, Lin, Huilan, Soh, Unice J.K., Paing, May M., Montagne, William A., Meerloo, Timo, Trejo, JoAnn
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2012
Teme:
Research Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341166/
https://ncbi.nlm.nih.gov/pubmed/22547407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201110031
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