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AP-3 regulates PAR1 ubiquitin-independent MVB/lysosomal sorting via an ALIX-mediated pathway

The sorting of signaling receptors within the endocytic system is important for appropriate cellular responses. After activation, receptors are trafficked to early endosomes and either recycled or sorted to lysosomes and degraded. Most receptors trafficked to lysosomes are modified with ubiquitin an...

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Main Authors: Dores, Michael R., Paing, May M., Lin, Huilan, Montagne, William A., Marchese, Adriano, Trejo, JoAnn
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442409/
https://ncbi.nlm.nih.gov/pubmed/22833563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-03-0251
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