RNA-Free and Ribonucleoprotein-Associated Influenza Virus Polymerases Directly Bind the Serine-5-Phosphorylated Carboxyl-Terminal Domain of Host RNA Polymerase II

Influenza viruses subvert the transcriptional machinery of their hosts to synthesize their own viral mRNA. Ongoing transcription by cellular RNA polymerase II (Pol II) is required for viral mRNA synthesis. By a process known as cap snatching, the virus steals short 5′ capped RNA fragments from host...

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Bibliographic Details
Published in:J Virol
Main Authors: Martínez-Alonso, Mónica, Hengrung, Narin, Fodor, Ervin
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907247/
https://ncbi.nlm.nih.gov/pubmed/27099314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00494-16
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