Oxidation of RyR2 Has a Biphasic Effect on the Threshold for Store Overload-Induced Calcium Release

At the single-channel level, oxidation of the cardiac ryanodine receptor (RyR2) is known to activate and inhibit the channel depending on the level of oxidation. However, the mechanisms through which these changes alter the activity of RyR2 in a cellular setting are poorly understood. In this study,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biophys J
Prif Awduron: Waddell, Helen M.M., Zhang, Joe Z., Hoeksema, Katie J., McLachlan, Julia J., McLay, Janet C., Jones, Peter P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Biophysical Society 2016
Pynciau:
Channels and Transporters
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906161/
https://ncbi.nlm.nih.gov/pubmed/27276257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.04.036
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg