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Oxidation of RyR2 Has a Biphasic Effect on the Threshold for Store Overload-Induced Calcium Release
At the single-channel level, oxidation of the cardiac ryanodine receptor (RyR2) is known to activate and inhibit the channel depending on the level of oxidation. However, the mechanisms through which these changes alter the activity of RyR2 in a cellular setting are poorly understood. In this study,...
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Publicado no: | Biophys J |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Biophysical Society
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4906161/ https://ncbi.nlm.nih.gov/pubmed/27276257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.04.036 |
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