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A Simple Model of Protein Domain Swapping in Crowded Cellular Environments

Domain swapping in proteins is an important mechanism of functional and structural innovation. However, despite its ubiquity and importance, the physical mechanisms that lead to domain swapping are poorly understood. Here, we present a simple two-dimensional coarse-grained model of protein domain sw...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biophys J
Prif Awduron: Woodard, Jaie C., Dunatunga, Sachith, Shakhnovich, Eugene I.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Biophysical Society 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906159/
https://ncbi.nlm.nih.gov/pubmed/27276255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.04.033
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