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A Simple Model of Protein Domain Swapping in Crowded Cellular Environments

Domain swapping in proteins is an important mechanism of functional and structural innovation. However, despite its ubiquity and importance, the physical mechanisms that lead to domain swapping are poorly understood. Here, we present a simple two-dimensional coarse-grained model of protein domain sw...

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Détails bibliographiques
Publié dans:Biophys J
Auteurs principaux: Woodard, Jaie C., Dunatunga, Sachith, Shakhnovich, Eugene I.
Format: Artigo
Langue:Inglês
Publié: The Biophysical Society 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906159/
https://ncbi.nlm.nih.gov/pubmed/27276255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.04.033
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