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A Simple Model of Protein Domain Swapping in Crowded Cellular Environments

Domain swapping in proteins is an important mechanism of functional and structural innovation. However, despite its ubiquity and importance, the physical mechanisms that lead to domain swapping are poorly understood. Here, we present a simple two-dimensional coarse-grained model of protein domain sw...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Woodard, Jaie C., Dunatunga, Sachith, Shakhnovich, Eugene I.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906159/
https://ncbi.nlm.nih.gov/pubmed/27276255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.04.033
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