Influence of Glu/Arg, Asp/Arg, and Glu/Lys Salt Bridges on α-Helical Stability and Folding Kinetics

Using a combination of ultraviolet circular dichroism, temperature-jump transient-infrared spectroscopy, and molecular dynamics simulations, we investigate the effect of salt bridges between different types of charged amino-acid residue pairs on α-helix folding. We determine the stability and the fo...

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Bibliographic Details
Published in:Biophys J
Main Authors: Meuzelaar, Heleen, Vreede, Jocelyne, Woutersen, Sander
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2016
Subjects:
Proteins
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906143/
https://ncbi.nlm.nih.gov/pubmed/27276251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.04.015
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