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Helix stabilization by Glu-...Lys+ salt bridges in short peptides of de novo design.

Four alanine-based peptides were designed, synthesized, and tested by circular dichroism for alpha-helix formation in H2O. Each peptide has three glutamic/lysine residue pairs, is 16 or 17 amino acids long, and has blocked alpha-NH2 and alpha-COOH groups. In one set of peptides ("i+4"), th...

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Autors principals: Marqusee, S, Baldwin, R L
Format: Artigo
Idioma:Inglês
Publicat: 1987
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC299658/
https://ncbi.nlm.nih.gov/pubmed/3122208
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