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ABCC4 Is a Determinant of Cytarabine‐Induced Cytotoxicity and Myelosuppression
Resistance to cytarabine remains a major challenge in the treatment of acute myeloid leukemia (AML). Based on previous studies implicating ABCC4/MRP4 in the transport of nucleosides, we hypothesized that cytarabine is sensitive to ABCC4‐mediated efflux, thereby decreasing its cytotoxic response agai...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Clin Transl Sci |
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| Κύριοι συγγραφείς: | , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
John Wiley and Sons Inc.
2016
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4905720/ https://ncbi.nlm.nih.gov/pubmed/26842729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12366 |
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