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Mathematical models for cytarabine-derived myelosuppression in acute myeloid leukaemia

We investigate the personalisation and prediction accuracy of mathematical models for white blood cell (WBC) count dynamics during consolidation treatment using intermediate or high-dose cytarabine (Ara-C) in acute myeloid leukaemia (AML). Ara-C is the clinically most relevant cytotoxic agent for AM...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Jost, Felix, Schalk, Enrico, Rinke, Kristine, Fischer, Thomas, Sager, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6602180/
https://ncbi.nlm.nih.gov/pubmed/31260449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204540
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