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Discovery of Small-Molecule Modulators of the Human Y(4) Receptor

The human neuropeptide Y(4) receptor (Y(4)R) and its native ligand, pancreatic polypeptide, are critically involved in the regulation of human metabolism by signaling satiety and regulating food intake, as well as increasing energy expenditure. Thus, this receptor represents a putative target for tr...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Sliwoski, Gregory, Schubert, Mario, Stichel, Jan, Weaver, David, Beck-Sickinger, Annette G., Meiler, Jens
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905667/
https://ncbi.nlm.nih.gov/pubmed/27294784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157146
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